According to Dr. Sadati, Autologous fat (patient's own fat) meets many of the criteria of an ideal material for use in tissue augmentation procedures. He is a cosmetic and reconstructive surgeon located in Newport Beach, Ca. With change of people preceptions, many indiviuals are in search of a natural look and a natural material to enhance their bodies. Dr. Sadati is a pioneer in the field of tissue transfer, his patients travel from state of California, Washington, Oregon, Idaho, Montana, northern California, Arizona, and as far as Canada and Alaska to have fat grafting.
It is well known in the field of surgical transplantation that augmentation with autologous tissue is the Ideal material. It is also well established that autologous tissue will survive the transfer. By definition, an ideal graft tissue should be readily available, not get rejected by body, low donor site morbidity, and a lack of disease transmission. Autologous fat grafting meets all of these criteria. Fat graft survival has been well documented, however there are some surgeons reporting that their fat transfer survival is unpredictable. At the Gallery of Cosmetic Surgery, where Dr. Sadati is in private practice, surgeons have been studying the effects of addition of Platelet Rich Plasma (PRP) to autologous fat since the late 1990s. Their clinical studies on free fat transfer have shown excellent outcomes and long lasting results, based on the principle that PRP, as a material rich in growth factors and cytokines, would have the potential of improved fat cell viability, as well as accelerate the wound-healing cascade. They have developed and published algorithms for free fat transfer with PRP in the American Journal of Cosmetic Surgery. According to their studies, addition of PRP will increase the retention of the transplanted fat cells as well as the rate of revascularization (growth of new blood vessels near the fat cells) for nutrition and oxygenation. In addition to use of PRP-enriched fat, careful attention to the technical harvesting, handling, and transfer protocols are critical to achieving reproducible success with autologous fat transplantation. In that regard, Dr. Sadati suggested important elements of his techniques include careful selection of donor sites, and use of a minimal traumatic low pressure harvest and transfer. He feels that fat is best collected from primary, genetically determined problem deposit sites of individual patients, using a tumescent saline technique. Significant improvement in the latest equipment has been advanced in improved closed syringe systems (Cell Friendly, Tulip Medical), using proprietary super-polished (internal), and coated (exterior) surfaces to minimize cell trauma during harvest and transfer.
Which body contours can be enhanced with Autologous Fat Transfer?
- Breasts (instead of saline implants)
- Buttocks
- Calves
- Cheek and chin
- Aging depressions of temporal region
- Brow lines
- Lips
- Nasolabial Folds
- Wrinkles of the face
- Wrinkles on the Back of hands
What is PRP? Platelet Rich Plasma (PRP) is rich in variety of valuable natural growth factors such as PDGF (Platelets Derived Growth Factor), and TGF-β1 (Transforming Growth Factor β1). These Growth factors are known to be important in initiation and progression of wound healing.
Where does PRP come from? From patients own blood. At the time of procedure about 30 cc of patient's blood is centrifuged to separate platelet rich plasma from the hemoglobin.
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